FNBP1 anticorps (AA 331-430) (AbBy Fluor® 555)
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- Antigène Voir toutes FNBP1 Anticorps
- FNBP1 (Formin Binding Protein 1 (FNBP1))
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Épitope
- AA 331-430
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Reactivité
- Poisson-ballons, Xenopus laevis
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FNBP1 est conjugé à/à la AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Poisson-ballons, Xenopus laevis
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Zebrafish
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human FBP17
- Isotype
- IgG
- Top Product
- Discover our top product FNBP1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- FNBP1 (Formin Binding Protein 1 (FNBP1))
- Autre désignation
- FBP17 (FNBP1 Produits)
- Synonymes
- anticorps MGC122623, anticorps MGC146466, anticorps FBP17, anticorps 1110057E06Rik, anticorps 2210010H06Rik, anticorps FBP1, anticorps Fbp17, anticorps formin binding protein 1, anticorps formin binding protein 1 L homeolog, anticorps FNBP1, anticorps fnbp1, anticorps Fnbp1, anticorps fnbp1.L
- Sujet
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Synonyms: FBP1, FBP17, FNBP1, FNBP1_HUMAN, Formin binding protein 1, Formin binding protein 17, Formin-binding protein 1, Formin-binding protein 17, hFBP17, KIAA0554, MGC126804.
Background: FNBP1 is a 617 amino acid protein that localizes to a variety of locations within the cell, including the cytoplasm, cytoskeleton, lysosome and the cell cortex, and contains one FCH domain, one REM repeat and one SH3 domain. Expressed at high levels in respiratory, reproductive and urinary systems, as well as in brown adipose tissue and epithelial cells of the gastrointestinal tract, FNBP1 interacts with Rho 7 and links the Actin cytoskeleton with Rho 7 signaling, playing a crucial role in membrane tubulation and cytoskeletal reorganization during endocytosis. Additionally, FNBP1, which exists as four alternatively spliced isoforms, enhances Actin polymerization and promotes membrane invagination and the formation of tubules. Chromosomal aberrations in the FNBP1 gene are associated with acute leukemias, suggesting a role for defective FNBP1 in carcinogenesis.
- ID gène
- 23048
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