SIX2 anticorps (AA 101-200) (AbBy Fluor® 555)
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- Antigène Voir toutes SIX2 Anticorps
- SIX2 (SIX Homeobox 2 (SIX2))
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Épitope
- AA 101-200
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SIX2 est conjugé à/à la AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SIX2
- Isotype
- IgG
- Top Product
- Discover our top product SIX2 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SIX2 (SIX Homeobox 2 (SIX2))
- Autre désignation
- SIX2 (SIX2 Produits)
- Synonymes
- anticorps six2-A, anticorps zgc:195089, anticorps zgc:195096, anticorps six2.1, anticorps wu:fj04e08, anticorps zgc:91945, anticorps SIX homeobox 2, anticorps sine oculis-related homeobox 2, anticorps SIX homeobox 2 S homeolog, anticorps SIX homeobox 2b, anticorps SIX homeobox 2a, anticorps SIX2, anticorps Six2, anticorps six2.S, anticorps six2b, anticorps six2a
- Sujet
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Synonyms: Homeobox protein SIX2, OTTHUMP00000201649, Sine oculis homeobox Drosophila homolog 2, Sine oculis homeobox homolog 2, Sine oculis homeobox homolog 2 Drosophila, SIX homeobox 2, Six2, SIX2_HUMAN.
Background: The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six2, Six4 (AREC3) and Six5 bind to the same DNA sequence, indicating that they may regulate the same target genes. Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, such as myogenin. It has been demonstrated that alterations to homeobox-containing genes may result in cancer. Six1 expression has been shown to be absent or low in normal adult tissues, although it is expressed in several tumor types, including breast carcinoma. Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint. Six2 is highly expressed in fetal tissues but expression is limited in adult tissues.
- ID gène
- 10736
- Pathways
- Protein targeting to Nucleus
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