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GAS41 anticorps (AA 151-227) (AbBy Fluor® 647)

Reactivité: Souris, Xenopus laevis WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN1698684
  • Antigène Tous les produits GAS41
    GAS41 (YEATS Domain Containing 4)
    Épitope
    • 14
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-227
    Reactivité
    • 51
    • 41
    • 15
    • 14
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Souris, Xenopus laevis
    Hôte
    • 55
    • 10
    Lapin
    Clonalité
    • 57
    • 8
    Polyclonal
    Conjugué
    • 28
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GAS41 est conjugé à/à la AbBy Fluor® 647
    Application
    • 49
    • 24
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris, Xenopus laevis
    Homologie
    Human,Rat,Cow,Horse,Chicken,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GAS41
    Isotype
    IgG
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GAS41 (YEATS Domain Containing 4)
    Autre désignation
    GAS41 (GAS41 Produits)
    Synonymes
    anticorps 4930573H17Rik, anticorps B230215M10Rik, anticorps GAS41, anticorps NUBI-1, anticorps YAF9, anticorps YEATS4, anticorps NuBI-1, anticorps RGD1305741, anticorps zgc:100841, anticorps MGC89432, anticorps CG9207, anticorps Dmel\\CG9207, anticorps dGas41, anticorps GB13136, anticorps GLIOMAS 41, anticorps K2N11.8, anticorps K2N11_8, anticorps TAF14B, anticorps TBP-ASSOCIATED FACTOR 14B, anticorps NV13456, anticorps YEATS domain containing 4, anticorps YEATS domain containing 4 S homeolog, anticorps CG9207 gene product from transcript CG9207-RA, anticorps YEATS domain-containing protein 4, anticorps YEATS family protein, anticorps Gas41, anticorps gas41 homologue, putative, anticorps putative gas41, anticorps YEATS4, anticorps Yeats4, anticorps yeats4.S, anticorps yeats4, anticorps Gas41, anticorps LOC412705, anticorps GAS41, anticorps Chro.20029, anticorps PB300718.00.0, anticorps PCHAS_122420, anticorps Smp_070760, anticorps LOC100121822
    Sujet

    Synonyms: 4930573H17Rik, B230215M10Rik, GAS 41, Gas41, glioma amplied sequence 41, Glioma-amplied sequence 41, glioma-amplied sequence-41, gliomaamplied sequence 41, gliomaamplied sequence41, NUBI 1, NuBI-1, NuBI1, NuMA binding protein 1, NuMA-binding protein 1, YAF9, YEATS domain containing 4, YEATS domain containing4, YEATS domain-containing protein 4, YEATS4, YETS4_HUMAN.

    Background: Gene amplification is associated with tumor stage and progression in human gliomas. Several amplified loci are identified and comprise multiple genes. The glioma amplified sequence 41 (GAS41) is an evolutionarily conserved eukaryotic protein found in diverse species. GAS41 is related to the AF-9 and ENL proteins, which are putative transcription factors in some acute leukemias, and interacts with a component of the nuclear matrix, NuMA, in interphase cells. GAS41 has a dotted staining pattern in interphase nuclei and a uniform distribution in mitotic cells. GAS41 is ubiquitously expressed, with the highest levels of expression in human brain. In neuroblastoma, GAS41 is located in the nucleoli, but not in the nucleoplasm. GAS41 also binds to the MLL fusion partner AF10, which is involved in two distinct chromosomal translocations associated with hematologic malignancy. In addition, GAS41 interacts with INI1 (Integrase Interactor), which is a human homologue of the yeast SNF5 protein, a component of the SWI/SNF complex. The GAS41 gene maps to human chromosome 12q13-q15.

    ID gène
    8089
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