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CHTOP anticorps (AA 31-130) (AbBy Fluor® 647)

CHTOP Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 647
N° du produit ABIN1698809
  • Antigène Voir toutes CHTOP Anticorps
    CHTOP (Chromatin Target of PRMT1 (CHTOP))
    Épitope
    • 14
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 31-130
    Reactivité
    • 28
    • 11
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 27
    • 3
    • 2
    Lapin
    Clonalité
    • 27
    • 5
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CHTOP est conjugé à/à la AbBy Fluor® 647
    Application
    • 14
    • 12
    • 12
    • 9
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C1orf77
    Isotype
    IgG
    Top Product
    Discover our top product CHTOP Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CHTOP (Chromatin Target of PRMT1 (CHTOP))
    Autre désignation
    C1orf77 (CHTOP Produits)
    Synonymes
    anticorps C1orf77, anticorps FL-SRAG, anticorps FOP, anticorps RP1-178F15.2, anticorps SRAG, anticorps SRAG-3, anticorps SRAG-5, anticorps pp7704, anticorps 2500003M10Rik, anticorps C81330, anticorps Fop, anticorps Srag, anticorps C25H1orf77, anticorps C3H1orf77, anticorps c1orf77, anticorps chtop, anticorps fop, anticorps srag, anticorps fb17a05, anticorps wu:fb17a05, anticorps wu:fi05e09, anticorps zgc:55292, anticorps zgc:153909, anticorps chromatin target of PRMT1, anticorps chromatin target of PRMT1 S homeolog, anticorps chromatin target of PRMT1 protein, anticorps chromatin target of PRMT1a, anticorps chromatin target of PRMT1b, anticorps CHTOP, anticorps Chtop, anticorps chtop.S, anticorps LOC100344922, anticorps chtopa, anticorps chtopb
    Sujet

    Synonyms: Chromatin target of PRMT1 protein, Chromosome 1 open reading frame 77, CHTOP, CHTOP_HUMAN, DKFZp547E1010, FOP, Friend of PRMT1 protein, MGC131924, MGC86949, OTTHUMP00000035122, OTTHUMP00000035123, Pp7704, RP1 178F15.2, Small arginine- and glycine-rich protein, Small protein rich in arginine and glycine, SRAG.

    Background: C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

    ID gène
    26097
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