EXTL3 anticorps (AA 351-450) (AbBy Fluor® 647)

N° du produit ABIN1699125

Détail du produit anti-EXTL3 anticorps (AbBy Fluor® 647)

Antigène: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Épitope: AA 351-450

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXTL3 est conjugé à/à la AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EXTL3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EXTL3

Antigène: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Autre désignation: EXTL3 (EXTL3 Produits)

Synonymes: anticorps BcDNA:LD21192, anticorps Botv, anticorps CG15110, anticorps DEXT3, anticorps DEXTL3, anticorps Dextl3, anticorps Dmel\\CG15110, anticorps Extl3, anticorps 2900009G18Rik, anticorps AU040105, anticorps Ext1l, anticorps mKIAA0519, anticorps BOTV, anticorps EXTL1L, anticorps EXTR1, anticorps REGR, anticorps RPR, anticorps Regr, anticorps brother of tout-velu, anticorps exostoses (multiple)-like 3, anticorps exostosin like glycosyltransferase 3, anticorps exostosin-like glycosyltransferase 3, anticorps botv, anticorps Extl3, anticorps EXTL3

Sujet:

Synonyms: botv, DKFZp686C2342, Exostoses multiple-like 3, Exostoses-like 3, Exostosin-like 3, EXT-related protein 1, EXTL1L, EXTL3, EXTL3_HUMAN, EXTR1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, KIAA0519, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3, REG, Reg receptor, REGR, RPR.

Background: EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus.

ID gène: 2137

Pathways: Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling