Cholera Toxin beta anticorps (Biotin)

N° du produit ABIN1699846

Cet anticorps Lapin Polyclonal détecte spécifiquement Cholera Toxin beta dans WB, ELISA, IHC (fro) et IHC (p). Il présente une réactivité avec des échantillons de Vibrio cholerae.

Aperçu rapide pour Cholera Toxin beta anticorps (Biotin) (ABIN1699846)

Antigène: Cholera Toxin beta

Reactivité: Vibrio cholerae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cholera Toxin beta est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Cholera Toxin beta anticorps (Biotin)

Réactivité croisée: Rat

Réactivité croisée (Details): Cholera Toxin Subunit B

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from CTXB/beta subunit Cholera Toxin

Isotype: IgG

Information d'application

Indications d'application: WB 1:100-1000
IHC-P 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Cholera Toxin beta

Antigène: Cholera Toxin beta

Sujet:

Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin beta chain, Cholera enterotoxin gamma chain, Cholera enterotoxin subunit B, Cholera toxin B protein, Choleragenoid, CTX B, CTXB, TOX B, TOXB, VC1456, CHTB_VIBCH.

Background: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

ID gène: 2613962