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CHI3L2 anticorps (AA 121-220) (Biotin)

CHI3L2 Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1700086
  • Antigène Voir toutes CHI3L2 Anticorps
    CHI3L2 (Chitinase 3-Like 2 (CHI3L2))
    Épitope
    • 14
    • 7
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220
    Reactivité
    • 48
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 44
    • 4
    Lapin
    Clonalité
    • 46
    • 2
    Polyclonal
    Conjugué
    • 20
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CHI3L2 est conjugé à/à la Biotin
    Application
    • 37
    • 16
    • 13
    • 13
    • 13
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human YKL39/CHI3L2
    Isotype
    IgG
    Top Product
    Discover our top product CHI3L2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    CHI3L2 (Chitinase 3-Like 2 (CHI3L2))
    Autre désignation
    YKL39/CHI3L2 (CHI3L2 Produits)
    Synonymes
    anticorps CHIL2, anticorps YKL-39, anticorps YKL39, anticorps chitinase 3 like 2, anticorps CHI3L2
    Sujet

    Synonyms: CH3L2_HUMAN, CHI3L2, Chitinase 3 like 2, Chitinase-3-like protein 2, Chondrocyte protein 39, OTTHUMP00000014028, YKL 39, YKL-39, YKL39.

    Background: YKL-39 is a 390 amino acid cartilage protein that belongs to the chitinase family of chitin-fragmenting hydrolases. Highly expressed in chondrocytes (cartilage cells) and synoviocytes (fibroblastic cells that line joint cavities), YKL-39 binds glycan structures with high affinity. Although related to bacterial chitinases, YKL-39 lacks the characteristic glutamate active site and, thus, does not have enzymatic chitinase activity. Patients affected with rheumatoid arthritis (RA) have autoimmunity against YKL-39, suggesting that YKL-39 is involved in osteoarthritic and/or rheumatoid joint disease. Additionally, YKL-39 is upregulated in early degenerative cartilage diseases (such as RA) and may be a marker of chondrocyte activation in these autoimmune conditions.

    ID gène
    7690
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