CMKLR1 anticorps (AA 171-280) (Biotin)

N° du produit ABIN1700137

Détail du produit anti-CMKLR1 anticorps (Biotin)

Antigène: CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

Épitope: AA 171-280

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMKLR1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Dog,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CMKLR1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CMKLR1

Antigène: CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

Autre désignation: CMKLR1 (CMKLR1 Produits)

Synonymes: anticorps CHEMERINR, anticorps ChemR23, anticorps DEZ, anticorps RVER1, anticorps Gpcr27, anticorps mcmklr1, anticorps si:ch211-240b21.3, anticorps CMLKR1, anticorps Cmklr-1, anticorps GPCR, anticorps chemerin chemokine-like receptor 1, anticorps chemokine-like receptor 1, anticorps CMKLR1, anticorps Cmklr1, anticorps cmklr1

Sujet:

Synonyms: Chemokine receptor-like 1, CHEMR23, ChemR23, DEZ, Chemokine like receptor 1, G protein coupled receptor ChemR23, G protein coupled receptor DEZ, CML1_HUMAN , Orphan G protein coupled receptor.

Background: Chemokine-Like Receptor 1 (CMKLR1) is a serpentine transmembrane G-protein linked receptor. It is an orphan chemoattractant receptor, also known as ChemR23 or DEZ. CMKLR1 is expressed on the surface of monocyte-derived immature dendritic cells and peripheral plamacytoid dendritic (pDC) cells, but not on myeloid dendritic (mDC) cells, monocytes and lymphocytes. The expression of CMKLR1 on pDC is down-regulated after activation. Chemerin (TIG2) is a natural ligand of CMKLR1. The interaction of CMKLR1 with Chemerin induces pDC activation and chemotaxis. It has been shown that CMKLR1 is a coreceptor for several strains of SIV and HIV-1. CMKLR1 is a potential useful marker for distinguishing pDCs and mDCs.

ID gène: 1240