DOK7 anticorps (AA 21-120) (Biotin)
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- Antigène Voir toutes DOK7 Anticorps
- DOK7 (Docking Protein 7 (DOK7))
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Épitope
- AA 21-120
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DOK7 est conjugé à/à la Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DOK7
- Isotype
- IgG
- Top Product
- Discover our top product DOK7 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- DOK7 (Docking Protein 7 (DOK7))
- Autre désignation
- DOK7 (DOK7 Produits)
- Synonymes
- anticorps si:dkey-180b4.3, anticorps si:ch211-164d19.2, anticorps C4orf25, anticorps CMS1B, anticorps A930013K19Rik, anticorps AW049091, anticorps Dok-7, anticorps EF-12, anticorps Oit5, anticorps RGD1566416, anticorps dok-7, anticorps docking protein 7, anticorps DOK7, anticorps dok7, anticorps Dok7
- Sujet
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Synonyms: Docking protein 7, DOK 7, DOK7, DOK7_HUMAN, Downstream of tyrosine kinase 7, Protein Dok-7.
Background: The downstream of kinase family (Dok1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) recessively inherited disorders characterized by muscle weakness.
- Pathways
- Skeletal Muscle Fiber Development
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