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C1orf177 anticorps (AA 21-100) (Biotin)

C1ORF177 Reactivité: Humain ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1700214
  • Antigène Tous les produits C1orf177 (C1ORF177)
    C1orf177 (C1ORF177) (Chromosome 1 Open Reading Frame 177 (C1ORF177))
    Épitope
    • 14
    • 2
    • 1
    • 1
    AA 21-100
    Reactivité
    • 31
    • 19
    • 16
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 34
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp C1orf177 est conjugé à/à la Biotin
    Application
    • 26
    • 20
    • 13
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C1orf177
    Isotype
    IgG
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    C1orf177 (C1ORF177) (Chromosome 1 Open Reading Frame 177 (C1ORF177))
    Autre désignation
    C1orf177 (C1ORF177 Produits)
    Synonymes
    anticorps lymphocyte expansion molecule, anticorps lymphocyte expansion molecule L homeolog, anticorps LEXM, anticorps lexm.L
    Sujet

    Synonyms: Chromosome 1 open reading frame 177, FLJ40201, Hypothetical protein LOC163747, Uncharacterized protein C1orf177, CA177_HUMAN.

    Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf177 gene product has been provisionally designated C1orf177 pending further characterization. There are two isoforms of C1orf177 that are produced as a result of alternative splicing events.

    ID gène
    163747
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