CUTC anticorps (AA 201-273) (Biotin)

N° du produit ABIN1700254

Détail du produit anti-CUTC anticorps (Biotin)

Antigène: CUTC (CutC Copper Transporter Homolog (CUTC))

Épitope: AA 201-273

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CUTC est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CUTC

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CUTC

Antigène: CUTC (CutC Copper Transporter Homolog (CUTC))

Autre désignation: CUTC (CUTC Produits)

Synonymes: anticorps zgc:103406, anticorps RP11-483F11.3, anticorps 2310039I18Rik, anticorps AI326282, anticorps CGI-32, anticorps cutC copper transporter, anticorps cutC copper transporter homolog (E. coli), anticorps CUTC, anticorps cutc, anticorps Cutc

Sujet:

Synonyms: CGI 32, CGI32, Copper homeostasis protein cutC homolog, cutC, CutC copper transporter homolog E. coli, CUTC_HUMAN, RP11-483F11.3.

Background: Copper is an essential micronutrient used as a co-factor for several essential enzymes in all living organisms. Due to the high toxicity of copper, its metabolism is tightly regulated and defects in this regulation can cause Menkes (deficiency) or Wilson (accumulation) disease in various tissue. CUTC (cutC copper transporter homolog (E. coli)), also known as CGI-32, is a 273 amino acid protein belonging to the cutC family. CUTC is involved in copper homeostasis and is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.

ID gène: 51076

Pathways: Transition Metal Ion Homeostasis