DLG5 anticorps (AA 1801-1919) (Biotin)

N° du produit ABIN1700261

Détail du produit anti-DLG5 anticorps (Biotin)

Antigène: DLG5 (Discs, Large Homolog 5 (DLG5))

Épitope: AA 1801-1919

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLG5 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DLG5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DLG5

Antigène: DLG5 (Discs, Large Homolog 5 (DLG5))

Autre désignation: DLG5 (DLG5 Produits)

Synonymes: anticorps DLG5, anticorps dlg5, anticorps wu:fc28f03, anticorps LP-DLG, anticorps P-DLG5, anticorps PDLG, anticorps 4933429D20Rik, anticorps T25557, anticorps mKIAA0583, anticorps discs large MAGUK scaffold protein 5, anticorps discs, large homolog 5 (Drosophila), anticorps discs, large homolog 5a (Drosophila), anticorps DLG5, anticorps dlg5a, anticorps Dlg5

Sujet:

Synonyms: Discs large homolog 5 Drosophila, Discs large homolog 5, Discs large protein LP DLG, Discs large protein P dlg, Discs large protein P-dlg, Disks large homolog 5, DLG 5, DLG5, DLG5_HUMAN, KIAA0583, Large type of P DLG, LP DLG, P DLG5, PDLG, Placenta and prostate DLG.

Background: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family. MAGUK family members include the postsynaptic proteins PSD-93, DLG5, Pals1, PSD-95 (SAP 90), densin-180, NE-dlg (SAP 120), dlg-1 (SAP 97), GKAP (GK-associated protein), p55, the tight junction associated proteins ZO-1-3 and the caspase-associated recruitment domain (CARD) proteins CARD6, CARD8-12 and CARD14. DLG5, a cell-cell junction peripheral membrane protein, plays an important role in maintaining the structure of epithelial cell plasma membranes. It also plays an important part in transmitting extracellular signals to the cytoskeleton and the membrane. DLG5 which can interact with MPP1 and CTNNB1, is primarily expressed in prostate and placenta.