POLM anticorps (AA 261-360) (Biotin)

N° du produit ABIN1700263

Détail du produit anti-POLM anticorps (Biotin)

Antigène: POLM (Polymerase (DNA Directed), mu (POLM))

Épitope: AA 261-360

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLM est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DNA polymerase mu

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur POLM

Antigène: POLM (Polymerase (DNA Directed), mu (POLM))

Autre désignation: DNA polymerase mu (POLM Produits)

Synonymes: anticorps polmu, anticorps zgc:56122, anticorps POLM, anticorps Pol Mu, anticorps Tdt-N, anticorps AI462166, anticorps B230309I03Rik, anticorps polymerase (DNA directed), mu, anticorps DNA polymerase mu, anticorps polm, anticorps POLM, anticorps CC1G_09351, anticorps VDBG_09335, anticorps Polm

Sujet:

Synonyms: DNA Polymerase Mu, DNA-directed DNA polymerase mu, DNA-directed DNA/RNA polymerase mu, DPOLM_HUMAN, FLJ35482, Pol iota, Pol Mu, Polm, POLM protein, Polymerase DNA directed mu, Polymerase DNA directed mu, Tdt N, Tdt-N, TdtN, Terminal transferase.

Background: DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.

ID gène: 27434

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response