GART anticorps (AA 281-380) (Biotin)

N° du produit ABIN1700302

Détail du produit anti-GART anticorps (Biotin)

Antigène: GART (Phosphoribosylglycinamide Formyltransferase (GART))

Épitope: AA 281-380

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GART est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GART

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GART

Antigène: GART (Phosphoribosylglycinamide Formyltransferase (GART))

Autre désignation: GART (GART Produits)

Synonymes: anticorps Gaps, anticorps Prgs, anticorps AIRS, anticorps GARS, anticorps GART-A, anticorps gart, anticorps phosphoribosylglycinamide formyltransferase, anticorps phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, anticorps phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase L homeolog, anticorps Gart, anticorps GART, anticorps gart.L

Sujet:

Synonyms: 5'-phosphoribosylglycinamide transformylase, AIR synthase, AIRS, GAR transformylase, GARS, GART, GART, GARTF, Glycinamide ribonucleotide synthetase, MGC47764, PAIS, PGFT, Phosphoribosyl-aminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide synthetase, PRGS, PUR2_HUMAN, Trifunctional purine biosynthetic protein adenosine 3.

Background: Purines are critical for energy metabolism, cell signaling and cell reproduction and also function as precursors for coenzymes, energy transfer molecules, regulatory factors and proteins involved in RNA and DNA synthesis. GART (GAR transformylase), also referred to as AIRS, GARS, PAIS, PGFT, PRGS or GARTF, is 1,010 amino acids in length and is a key folate-dependent trifunctional enzyme with phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity required for de novo purine biosynthesis. Cancer cells require considerable amounts of purines to sustain their accelerated growth and GART is, therefore, a target for cancer chemotherapy. GART is highly conserved in vertebrates. Two isoforms of GART are expressed due to alternative splicing events.

ID gène: 2618

UniProt: P22102