GCSH anticorps (AA 101-173) (Biotin)

N° du produit ABIN1700310

Détail du produit anti-GCSH anticorps (Biotin)

Antigène: GCSH (Glycine Cleavage System H Protein (GCSH))

Épitope: AA 101-173

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCSH est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GCSH

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GCSH

Antigène: GCSH (Glycine Cleavage System H Protein (GCSH))

Autre désignation: GCSH (GCSH Produits)

Synonymes: anticorps GCE, anticorps NKH, anticorps GCSH, anticorps H-PROTEIN, anticorps 1100001L02Rik, anticorps 5730591C18Rik, anticorps wu:fb14d10, anticorps wu:fw84b08, anticorps zgc:112535, anticorps BA5228, anticorps gce, anticorps gcsh, anticorps nkh, anticorps wu:fd56h06, anticorps zgc:110557, anticorps zgc:92732, anticorps glycine cleavage system protein H, anticorps glycine cleavage system protein H (aminomethyl carrier), anticorps glycine cleavage system lipoyl carrier protein GcvH, anticorps glycine cleavage system H protein, anticorps glycine cleavage system protein H (aminomethyl carrier), a, anticorps glycine cleavage system carrier of aminomethyl moiety GcvH, anticorps leucine rich repeat containing 34, anticorps glycine cleavage system protein H (aminomethyl carrier) L homeolog, anticorps glycine cleavage system protein H (aminomethyl carrier), b, anticorps GCSH, anticorps Gcsh, anticorps gcvH-2, anticorps gcvH, anticorps gcsha, anticorps LRRC34, anticorps gcsh.L, anticorps gcshb

Sujet:

Synonyms: GCE, GCSH, GCSH_HUMAN, Glycine cleavage system H protein, Glycine cleavage system H protein mitochondrial, Glycine cleavage system protein H aminomethyl carrier, Glycine cleavage system protein H, Lipoic acid containing protein, mitochondrial, Mitochondrial glycine cleavage system H protein, NKH.

Background: GCSH is a 173 amino acid mitochondrial protein that contains one lipoyl-binding domain and belongs to the gcvH family. Defects in the gene encoding GCSH are the cause of glycine encephalopathy (GCE), an autosomal recessive disease that is also referred to as non-ketotic hyperglycinemia (NKH). Characterized by severe neurological symptoms, patients with GCE have a large amount of glycine accumulated in their body fluids. The gene encoding GCSH maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome.

ID gène: 2653