MYCBPAP anticorps (AA 401-500) (Biotin)

N° du produit ABIN1700365

Détail du produit anti-MYCBPAP anticorps (Biotin)

Antigène: MYCBPAP (MYCBP Associated Protein (MYCBPAP))

Épitope: AA 401-500

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYCBPAP est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris, Rat

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MYCBPAP

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MYCBPAP

Antigène: MYCBPAP (MYCBP Associated Protein (MYCBPAP))

Autre désignation: MYCBPAP (MYCBPAP Produits)

Synonymes: anticorps AMAP-1, anticorps AMAP1, anticorps 4932408B01Rik, anticorps AW125474, anticorps COD106, anticorps MYCBP associated protein, anticorps Mycbp associated protein, anticorps MYCBPAP, anticorps Mycbpap

Sujet:

Synonyms: AMAM-1, AMAP-1, AMAP1, AMY-1-binding protein 1, DKFZp434N1415, MYBPP_HUMAN, MYCBP-associated protein, Mycbpap.

Background: AMAP-1 (AMY-1-binding protein 1), also known as AMAM-1 or MYCBPAP (MYCBP associated protein), is a 947 amino acid protein that is expressed specifically in testis and is involved in spermatogenesis and synaptic processes. AMAP-1 colocalizes with MYCBP (AMY-1) in cytoplasm and also localizes to membrane. The gene encoding AMAP-1 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

Pathways: Sensory Perception of Sound