RUSC1 anticorps (AA 281-380) (Biotin)

N° du produit ABIN1700389

Détail du produit anti-RUSC1 anticorps (Biotin)

Antigène: RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))

Épitope: AA 281-380

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUSC1 est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RUSC1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RUSC1

Antigène: RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))

Autre désignation: RUSC1 (RUSC1 Produits)

Synonymes: anticorps NESCA, anticorps 2210403N08Rik, anticorps AA408288, anticorps RUN and SH3 domain containing 1, anticorps RUSC1, anticorps Rusc1

Sujet:

Synonyms: DKFZp761A1822, Nesca, New molecule containing SH3 at the carboxy terminus, RUN and SH3 domain containing 1, RUN and SH3 domain containing protein 1, RUSC 1.

Background: RUSC1 is a 902 amino acid protein that contains a RUN domain and a SH3 domain. RUSC1?s RUN domain is necessary for NGF induced nuclear redistribution. RUSC1 is a putative signaling adapter which may play a role in neuronal differentiation. RUSC1 seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. RUSC2 (RUN and SH3 domain containing 2), also known as Iporin, is a 1,516 amino acid cytoplasmic protein that is widely expressed, with highest levels in brain and testis. The RUN domain of RUSC2 is required for interaction with Rab 1A, Rab 1B and GM130. It is thought that RUSC2 may possibly function as a connector between endoplasmic reticulum (ER) derived vesicle targets triggered by the Rab 1 GTPases and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions. RUSC2 also consists of a SH3 domain, suggesting a role in protein-protein interactions.