m1ip1 anticorps (AA 21-120) (Biotin)

N° du produit ABIN1700398

Détail du produit anti-m1ip1 anticorps (Biotin)

Antigène: m1ip1 (Mid1-Interacting Protein 1 (m1ip1))

Épitope: AA 21-120

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp m1ip1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLAP

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur m1ip1

Antigène: m1ip1 (Mid1-Interacting Protein 1 (m1ip1))

Autre désignation: SLAP (m1ip1 Produits)

Synonymes: anticorps MIG12, anticorps TB10, anticorps G12-like, anticorps S14R, anticorps STRAIT11499, anticorps THRSPL, anticorps 3110038L01Rik, anticorps Mig12, anticorps slap, anticorps mig12, anticorps thrspl, anticorps MGC80850, anticorps zgc:73223, anticorps g12, anticorps wu:fj32f05, anticorps thymosin beta 10, anticorps MID1 interacting protein 1, anticorps Mid1-interacting protein 1, anticorps Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)), anticorps MID1 interacting protein 1 S homeolog, anticorps MID1 interacting protein 1b, anticorps MID1 interacting protein 1a, anticorps TMSB10, anticorps MID1IP1, anticorps m1ip1, anticorps Mid1ip1, anticorps mid1ip1.S, anticorps mid1ip1b, anticorps mid1ip1a

Sujet:

Synonyms: hSLAP, SLA 1, SLA, SLA1, SLAP 1, SLAP, SLAP-1, SLAP1, SLAP1_HUMAN, Src like adapter, Src like adapter protein 1, Src like adaptor, SRC-like-adapter, Src-like-adapter protein 1.

Background: The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins. In general, it exists in association with catalytic domains, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, such as spectrin or Myosin, and in small adapter proteins, such as Crk and GRB2. SH3 domains are often accompanied by SH2 domains of 100 amino acids, which bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. The functions of SH3 domains are not as well defined. Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity. 3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120. A similar putative adapter protein, designated Slap, for Src-like adapter protein, has been cloned. Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family. The N- and C-termini, however, are unique.