CLIC2 anticorps (AA 51-150) (Biotin)

N° du produit ABIN1700468

Détail du produit anti-CLIC2 anticorps (Biotin)

Antigène: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Épitope: AA 51-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLIC2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Rat,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CLIC2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CLIC2

Antigène: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Autre désignation: CLIC2 (CLIC2 Produits)

Synonymes: anticorps zgc:92762, anticorps CLIC2, anticorps CLIC2b, anticorps MRXS32, anticorps XAP121, anticorps chloride intracellular channel 2, anticorps clic2, anticorps CLIC2, anticorps Clic2

Sujet:

Synonyms: Chloride intracellular channel 2, Chloride intracellular channel protein 2, CLIC 2b, CLIC2, CLIC2_HUMAN, CLIC2b, MRXS32, OTTHUMP00000196471, XAP 121, XAP121.

Background: Chloride channels (CLCs) regulate cellular traffic of chloride ions, a critical component of all living cells. CLCs are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. The putative 247 amino acid protein chloride intracellular channel 2 (CLIC2), also designated XAP121, shares 60 % identity with the CLIC1 protein and demonstrates expression in only fetal liver and adult skeletal muscle tissues. The CLIC2 gene maps to chromosome Xq28 and contains 6 exons. Because a direct association exists between a number of human chloride channel genes and a range of hereditary diseases, CLIC2 is a potential candidate for one of the many diseases linked to Xq28. The hereditary form of incontinentia pigmenti (IP2), for example, is a rare disorder characterized by abnormalities of the tissues and organs derived from the ectoderm and neuroectoderm that has been linked to Xq28

Pathways: Negative Regulation of Transporter Activity