Sp3 anticorps (AA 651-750) (Biotin)

N° du produit ABIN1700508

Détail du produit anti-Sp3 anticorps (Biotin)

Antigène: Sp3 (Sp3 Transcription Factor (Sp3))

Épitope: AA 651-750

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sp3 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SP3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Sp3

Antigène: Sp3 (Sp3 Transcription Factor (Sp3))

Autre désignation: SP3 (Sp3 Produits)

Synonymes: anticorps SPR2, anticorps D130027J01Rik, anticorps SP3, anticorps sp3, anticorps zgc:162922, anticorps Sp3 transcription factor, anticorps trans-acting transcription factor 3, anticorps sp3a transcription factor, anticorps Sp3 transcription factor S homeolog, anticorps SP3, anticorps Sp3, anticorps sp3a, anticorps sp3.S

Sujet:

Synonyms: D130027J01Rik, DKFZp686O1631, GC binding transcription factor Sp 3, GC binding transcription factor Sp3, MGC105187, OTTMUSP00000014207, SP 3, Sp 3 transcription factor, SP3, Sp3 transcription factor, SP3_HUMAN, Specicity protein 3, SPR 2, SPR-2, SPR2, Transcription factor SP 3, Transcription factor SP3, Transcription factor Sp3.

Background: The Sp transcription factor family includes Sp1, Sp2, Sp3 (SPR-2) and Sp4 (SPR-1). Sp transcription factors share similar structures but do not share simi-lar functions. All four proteins contain a highly conserved DNA-binding domain composed of three zinc fingers at the C-terminus. Sp family members bind the consensus sequence GGGGCGGGGC and other closely related sequences which are known as GC boxes. Sp1, Sp3 and Sp4 share a high affinity for GC boxes while Sp2 does not. Sp2 only weakly binds to GT boxes. Sp1, Sp2 and Sp3 are ubiquitously expressed, while Sp4 is abundantly expressed in brain with limited expression in other tissues. Sp1 and Sp3, but not Sp2 or Sp4, interact with E2, a regulatory element for the 4 subunit of neuronal nicotinic acetylcholine receptors. Sp3 is the only Sp member to inhibit Sp1 and Sp4 media