GEMIN7 anticorps (AA 21-120) (Biotin)

N° du produit ABIN1700552

Détail du produit anti-GEMIN7 anticorps (Biotin)

Antigène: GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))

Épitope: AA 21-120

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEMIN7 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Gemin 7

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GEMIN7

Antigène: GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))

Autre désignation: Gemin 7 (GEMIN7 Produits)

Synonymes: anticorps SIP3, anticorps GEMIN7, anticorps Gemin7, anticorps 2400008I04Rik, anticorps AI120175, anticorps AI461688, anticorps gem nuclear organelle associated protein 7, anticorps gem (nuclear organelle) associated protein 7, anticorps GEMIN7, anticorps Gemin7

Sujet:

Synonyms: SIP3, Gemin7, Gemin-7, GEMI7_HUMAN.

Background: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.

ID gène: 79760

Pathways: Ribonucleoprotein Complex Subunit Organization