POLL anticorps (AA 475-575) (Biotin)
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- Antigène Voir toutes POLL Anticorps
- POLL (Polymerase (DNA Directed), lambda (POLL))
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Épitope
- AA 475-575
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp POLL est conjugé à/à la Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DNA Polymerase lambda
- Isotype
- IgG
- Top Product
- Discover our top product POLL Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- POLL (Polymerase (DNA Directed), lambda (POLL))
- Autre désignation
- DNA Polymerase lambda (POLL Produits)
- Synonymes
- anticorps T10O24.13, anticorps T10O24_13, anticorps zgc:66320, anticorps zgc:77901, anticorps wu:fe49a04, anticorps beta-n, anticorps pol-kappa, anticorps BETAN, anticorps POLKAPPA, anticorps 1110003P06Rik, anticorps AV007317, anticorps DNA polymerase lambda (POLL), anticorps DNA polymerase lambda, anticorps polymerase (DNA directed), lambda, anticorps polymerase (DNA) lambda, anticorps Pol{lambda}, anticorps PTRG_00468, anticorps poll, anticorps POLL, anticorps MCYG_03796, anticorps LOC9325878, anticorps MGYG_02138, anticorps Poll
- Sujet
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Synonyms: BETA N, BETAN, DNA directed DNA polymerase lambda, DNA polymerase beta 2, DNA polymerase beta-2, DNA polymerase kappa, DNA polymerase kappa DNA polymerase beta N, DNA polymerase lambda, DNA polymerase lamda2, DPOLL_HUMAN, EC 2.7.7.7,EC 4.2.99., FLJ46002, OTTHUMP00000020321, OTTHUMP00000020323, OTTHUMP00000059179, Pol beta2, POL KAPPA, Pol Lambda, POLKAPPA, POLL, Polymerase DNA directed lambda.
Background: DNA polymerase lambda (pol lambda), also designated DNA polymerase lambda or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol lambda is a member of the DNA polymerase type-X family. Pol lambda extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol ?may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol lambda and thus influences the ability of pol ?to synthesize DNA.
- ID gène
- 27343
- Pathways
- Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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