GC-Rich Promoter Binding Protein 1 (GPBP1) (AA 11-110) anticorps (Biotin)

N° du produit ABIN1700690

Détail du produit

Antigène: GC-Rich Promoter Binding Protein 1 (GPBP1)

Épitope: AA 11-110

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GPBP1/Vasculin

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détail du antigène

Antigène: GC-Rich Promoter Binding Protein 1 (GPBP1)

Autre désignation: GPBP1/Vasculin (GPBP1 Produits)

Synonymes: anticorps MGC80437, anticorps Vasculin, anticorps DKFZp459A203, anticorps GPBP, anticorps SSH6, anticorps VASCULIN, anticorps 1700034P14Rik, anticorps AU019836, anticorps D230035M11Rik, anticorps Gpbp, anticorps mGPBP, anticorps RGD1305492, anticorps GC-rich promoter binding protein 1 L homeolog, anticorps GC-rich promoter binding protein 1, anticorps gpbp1.L, anticorps gpbp1, anticorps GPBP1, anticorps Gpbp1

Sujet:

Synonyms: DKFZp761C169, GC rich promoter binding protein 1, GC-rich promoter-binding protein 1, GPBP, Gpbp1, GPBP1_HUMAN, MGC126339, SSH6, Vascular wall linked, Vascular wall-linked protein, Vasculin.

Background: Vascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.

ID gène: 65056