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PTCHD2 anticorps (AA 401-500) (Biotin)

PTCHD2 Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1700721
  • Antigène Voir toutes PTCHD2 Anticorps
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Épitope
    • 14
    • 9
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    Reactivité
    • 38
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    Humain
    Hôte
    • 38
    Lapin
    Clonalité
    • 38
    Polyclonal
    Conjugué
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PTCHD2 est conjugé à/à la Biotin
    Application
    • 34
    • 18
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PTCHD2/DISP3
    Isotype
    IgG
    Top Product
    Discover our top product PTCHD2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Autre désignation
    PTCHD2/DISP3 (PTCHD2 Produits)
    Synonymes
    anticorps DISP3, anticorps G630052C06Rik, anticorps RNDEu-2, anticorps RGD1305820, anticorps dispatched RND transporter family member 3, anticorps patched domain-containing protein 2, anticorps si:dkey-32e23.6, anticorps DISP3, anticorps LOC100082708, anticorps si:dkey-32e23.6, anticorps disp3, anticorps Disp3
    Sujet

    Synonyms: DISP3, Dispatched, drosophila, homolog of, 3, G630052C06Rik, hCG_24779, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3, Ptchd2, PTHD2_HUMAN, RGD1305820, RND-type protein RNDEu-2, RNDEu-2, patched domain containing 2, RP23-157B15.1.

    Background: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

    ID gène
    57540
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