RBM15 anticorps (AA 151-250) (Biotin)

N° du produit ABIN1700724

Détail du produit anti-RBM15 anticorps (Biotin)

Antigène: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Épitope: AA 151-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM15 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RBM15

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RBM15

Antigène: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Autre désignation: RBM15/SPEN (RBM15 Produits)

Synonymes: anticorps MGC83913, anticorps im:7139999, anticorps OTT, anticorps OTT1, anticorps SPEN, anticorps C230088J01Rik, anticorps mKIAA1438, anticorps RNA binding motif protein 15, anticorps RNA binding motif protein 15 S homeolog, anticorps RBM15, anticorps rbm15.S, anticorps rbm15, anticorps Rbm15

Sujet:

Synonyms: One twenty two protein, OTT, OTT1, SPEN, RNA binding mot protein 15, RBM15_HUMAN.

Background: RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.