SNX5 anticorps (AA 2-75) (Biotin)

N° du produit ABIN1700730

Détail du produit anti-SNX5 anticorps (Biotin)

Antigène: SNX5 (Sorting Nexin 5 (SNX5))

Épitope: AA 2-75

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX5 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SNX5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SNX5

Antigène: SNX5 (Sorting Nexin 5 (SNX5))

Autre désignation: SNX5 (SNX5 Produits)

Synonymes: anticorps 0910001N05Rik, anticorps 1810032P22Rik, anticorps AU019504, anticorps D2Ertd52e, anticorps id:ibd5091, anticorps wu:fa66c10, anticorps wu:fi28h04, anticorps zgc:55769, anticorps SNX5, anticorps snx5, anticorps sorting nexin 5, anticorps sorting nexin 5 S homeolog, anticorps SNX5, anticorps Snx5, anticorps snx5.S, anticorps snx5

Sujet:

Synonyms: 0910001N05Rik, 1810032P22Rik, AU019504, D2Ertd52e, FLJ10931, OTTHUMP00000030340, OTTHUMP00000062927, OTTMUSP00000003367, OTTMUSP00000003368, RP11-504H3.2, RP23-35E16.2, snoRNA MBI-43, SNX 5, SNX5, SNX5_HUMAN, Sorting nexin 5, Sorting nexin-5.

Background: Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

ID gène: 27131