GCHFR anticorps (AA 21-60) (Biotin)

N° du produit ABIN1700812

Détail du produit anti-GCHFR anticorps (Biotin)

Antigène: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Épitope: AA 21-60

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCHFR est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GCHFR

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GCHFR

Antigène: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Autre désignation: GCHFR (GCHFR Produits)

Synonymes: anticorps GFRP, anticorps HsT16933, anticorps P35, anticorps 2010323F13Rik, anticorps GTP cyclohydrolase I feedback regulator, anticorps GCHFR, anticorps Gchfr

Sujet:

Synonyms: GCHFR, GFRP, GFRP_HUMAN, GTP cyclohydrolase 1 feedback regulatory protein, GTP cyclohydrolase I feedback regulator, GTP cyclohydrolase I feedback regulatory protein, HsT16933, MGC138467, MGC138469, p35.

Background: GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. The molecular weight of GFRP is approximately 9.5 kDa although cross-linking experiments have shown that GFRP is usually found as a homodimer or as a pentamer. 15q15.

ID gène: 2644