Manic Fringe anticorps (AA 221-321) (Biotin)

N° du produit ABIN1700893

Détail du produit anti-Manic Fringe anticorps (Biotin)

Antigène: Manic Fringe (MFNG) (MFNG)

Épitope: AA 221-321

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Manic Fringe est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Horse,Chimpanzee

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Manic Fringe/MFNG

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Manic Fringe

Antigène: Manic Fringe (MFNG) (MFNG)

Autre désignation: Manic Fringe/MFNG (MFNG Produits)

Synonymes: anticorps AW546563, anticorps MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, anticorps MFNG, anticorps Mfng

Sujet:

Synonyms: 3-N-acetylglucosaminyltransferase manic fringe, Beta-1, Beta-1,3-N-acetylglucosaminyltransferase manic fringe, MFNG, MFNG_HUMAN, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.

Background: Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many adult tissues. Radical fringe plays a key role in the development of the limb bud. Lunatic fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice.

ID gène: 4242

Pathways: Signalisation Notch