GEMIN4 anticorps (AA 251-350) (Biotin)

N° du produit ABIN1700953

Détail du produit anti-GEMIN4 anticorps (Biotin)

Antigène: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Épitope: AA 251-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEMIN4 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Gemin 4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GEMIN4

Antigène: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Autre désignation: Gemin 4 (GEMIN4 Produits)

Synonymes: anticorps HC56, anticorps HCAP1, anticorps HHRF-1, anticorps p97, anticorps 4932415L08Rik, anticorps AU015359, anticorps im:7143815, anticorps wu:fc41c09, anticorps zgc:110169, anticorps GEMIN4, anticorps RGD1563715, anticorps gem nuclear organelle associated protein 4, anticorps gem (nuclear organelle) associated protein 4, anticorps GEMIN4, anticorps Gemin4, anticorps gemin4

Sujet:

Synonyms: Gemin4, Gemin-4, Component of gems 4, Gem associated protein 4, HC56, HHRF 1, GEMI4_HUMAN.

Background: Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.

ID gène: 50628

Pathways: Ribonucleoprotein Complex Subunit Organization