ADRM1 anticorps (AA 21-120) (Biotin)

N° du produit ABIN1700985

Détail du produit anti-ADRM1 anticorps (Biotin)

Antigène: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Épitope: AA 21-120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRM1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ADRM1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ADRM1

Antigène: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Autre désignation: ADRM1 (Adrm1 Produits)

Synonymes: anticorps arm-1, anticorps gp110, anticorps rpn13, anticorps xoom, anticorps ADRM1, anticorps adrm1, anticorps ARM-1, anticorps ARM1, anticorps GP110, anticorps 1110063P18Rik, anticorps 2510006J17Rik, anticorps AA408205, anticorps AU043535, anticorps Arm1, anticorps Gp110, anticorps Rpn13, anticorps adrm1a, anticorps adrm1b, anticorps fa12d09, anticorps wu:fa10g10, anticorps wu:fa12d09, anticorps zgc:56107, anticorps zgc:77256, anticorps adhesion regulating molecule 1, anticorps ADRM1, anticorps 19S proteasome regulatory subunit, anticorps ADRM1 protein, anticorps adrm1, anticorps ADRM1, anticorps CpipJ_CPIJ002929, anticorps SJAG_04211, anticorps Adrm1

Sujet:

Synonyms: 110 kDa cell membrane glycoprotein, adhesion regulating molecule 1, Adhesion-regulating molecule 1, ADRM 1, Adrm1, ADRM1_HUMAN, ARM 1, ARM-1, ARM1, GP110, hRpn13, Mr 110,000 surface antigen, Proteasomal ubiquitin receptor ADRM1, proteasome regulatory particle non ATPase 13, Proteasome regulatory particle non-ATPase 13, Regulatory particle non ATPase 13, Rpn13, Rpn13 homolog.

Background: ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.

ID gène: 11047

Pathways: Positive Regulation of Endopeptidase Activity