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Glutaredoxin 2 anticorps (AA 101-164) (Biotin)

GRX2 Reactivité: Humain, Rat WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1701049
  • Antigène Voir toutes Glutaredoxin 2 (GRX2) Anticorps
    Glutaredoxin 2 (GRX2)
    Épitope
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 101-164
    Reactivité
    • 45
    • 22
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Rat
    Hôte
    • 39
    • 6
    Lapin
    Clonalité
    • 43
    • 2
    Polyclonal
    Conjugué
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Glutaredoxin 2 est conjugé à/à la Biotin
    Application
    • 32
    • 21
    • 13
    • 13
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse,Dog,Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Glutaredoxin 2
    Isotype
    IgG
    Top Product
    Discover our top product GRX2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    Glutaredoxin 2 (GRX2)
    Autre désignation
    Glutaredoxin 2 (GRX2 Produits)
    Synonymes
    anticorps ECK1049, anticorps JW1051, anticorps CGI-133, anticorps GRX2, anticorps 1700010P22Rik, anticorps AI645710, anticorps Grx2, anticorps glutaredoxin 2 (Grx2), anticorps glutaredoxin Grx2, anticorps thioredoxin, anticorps glutaredoxin 2, anticorps glutaredoxin 2 (thioltransferase), anticorps grxB, anticorps grx2, anticorps AF_RS10790, anticorps GLRX2, anticorps Glrx2
    Sujet

    Synonyms: GRX2, CGI-133, Glutaredoxin-2, mitochondrial, GLRX2

    Background: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

    ID gène
    51022
    UniProt
    Q9NS18
    Pathways
    Cell RedoxHomeostasis
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