FFAR1 anticorps (AA 121-220) (Biotin)
-
- Antigène Voir toutes FFAR1 Anticorps
- FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
-
Épitope
- AA 121-220
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp FFAR1 est conjugé à/à la Biotin
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GPR40
- Isotype
- IgG
- Top Product
- Discover our top product FFAR1 Anticorps primaire
-
-
- Indications d'application
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
-
- Antigène
- FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
- Autre désignation
- GPR40 (FFAR1 Produits)
- Synonymes
- anticorps FFAR1, anticorps GPR40, anticorps FFA1R, anticorps GPCR40, anticorps Gpr40, anticorps free fatty acid receptor 1, anticorps FFAR1, anticorps Ffar1
- Sujet
-
Synonyms: FFA1R, GPR40, GPCR40, Free fatty acid receptor 1, G-protein coupled receptor 40, FFAR1
Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.
- ID gène
- 2864
- UniProt
- O14842
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
-