TYROBP anticorps (AA 31-113) (Biotin)
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- Antigène Voir toutes TYROBP Anticorps
- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
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Épitope
- AA 31-113
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TYROBP est conjugé à/à la Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human DAP12
- Isotype
- IgG
- Top Product
- Discover our top product TYROBP Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
- Autre désignation
- DAP12 (TYROBP Produits)
- Synonymes
- anticorps TYROBP, anticorps DAP12, anticorps tyrpbp, anticorps Karap, anticorps KARAP, anticorps PLOSL, anticorps Ly83, anticorps dap12, anticorps TYRO protein tyrosine kinase binding protein, anticorps Tyro protein tyrosine kinase binding protein, anticorps TYROBP, anticorps tyrobp, anticorps Tyrobp
- Sujet
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Synonyms: DAP 12, DAP12, DNAX activation protein 12, DNAX-activation protein 12, KAR-associated protein, KARAP, Killer activating receptor associated protein, Killer-activating receptor-associated protein, PLOSL, TYOBP_HUMAN, TYRO protein tyrosine kinase binding protein, TYRO protein tyrosine kinase-binding protein, TYROBP.
Background: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]
- ID gène
- 7305
- UniProt
- O43914
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