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DYRK2 anticorps (AA 425-480) (Biotin)

DYRK2 Reactivité: Souris, Rat WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1701231
  • Antigène Voir toutes DYRK2 Anticorps
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Épitope
    • 14
    • 11
    • 8
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 425-480
    Reactivité
    • 43
    • 31
    • 21
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 55
    • 7
    • 1
    Lapin
    Clonalité
    • 56
    • 7
    Polyclonal
    Conjugué
    • 27
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DYRK2 est conjugé à/à la Biotin
    Application
    • 56
    • 32
    • 27
    • 13
    • 13
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DYRK2
    Isotype
    IgG
    Top Product
    Discover our top product DYRK2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Autre désignation
    DYRK2 (DYRK2 Produits)
    Synonymes
    anticorps DYRK2, anticorps fc18c09, anticorps si:ch211-266a5.8, anticorps wu:fa09g03, anticorps wu:fc18c09, anticorps 1810038L18Rik, anticorps dual specificity tyrosine phosphorylation regulated kinase 2, anticorps dual specificity tyrosine-phosphorylation-regulated kinase 2, anticorps dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2, anticorps DYRK2, anticorps CpipJ_CPIJ014802, anticorps dyrk2, anticorps Dyrk2
    Sujet

    Synonyms: 1810038L18Rik, Dual specicity tyrosine Y phosphorylation regulated kinase 2, Dual specicity tyrosine phosphorylation regulated kinase 2, Dual specicity tyrosine-phosphorylation-regulated kinase 2, DYRK2, DYRK2_HUMAN, EC 2.7.12.1, FLJ21217, FLJ21365.

    Background: Dyrk is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis (13). Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation (1). Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases (4). Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dryk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions (4). Dyrk1A is a candidate gene that may be involved in Downs syndrome, and it has been found to be somewhat overexpressed in Downs syndrome (1,5). Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus (4). Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland (1). The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively (4).

    ID gène
    8445
    Pathways
    Regulation of Carbohydrate Metabolic Process
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