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EYA2 anticorps (AA 201-300) (Biotin)

EYA2 Reactivité: Rat WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1701245
  • Antigène Voir toutes EYA2 Anticorps
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Épitope
    • 14
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reactivité
    • 42
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Rat
    Hôte
    • 53
    • 3
    Lapin
    Clonalité
    • 54
    • 2
    Polyclonal
    Conjugué
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EYA2 est conjugé à/à la Biotin
    Application
    • 43
    • 25
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EYA2
    Isotype
    IgG
    Top Product
    Discover our top product EYA2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Autre désignation
    EYA2 (EYA2 Produits)
    Synonymes
    anticorps EYA2, anticorps zgc:92279, anticorps eab1, anticorps Eab1, anticorps EAB1, anticorps EYA transcriptional coactivator and phosphatase 2, anticorps EYA2, anticorps eya2, anticorps Eya2
    Sujet

    Synonyms: EAB 1, EAB1, EYA 2, EYA2, EYA2_HUMAN, eyes absent 2 homolog Drosophila, Eyes absent homolog 2, Translation of this uORF probably lowers the translation efficiency of EYA2.

    Background: A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.

    ID gène
    2139
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