SRSF10 anticorps (AA 151-250) (Biotin)

N° du produit ABIN1701276

Détail du produit anti-SRSF10 anticorps (Biotin)

Antigène: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Épitope: AA 151-250

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRSF10 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FUSIP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SRSF10

Antigène: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Autre désignation: FUSIP1 (SRSF10 Produits)

Synonymes: anticorps FUSIP1, anticorps SFRS13A, anticorps FUSIP2, anticorps NSSR, anticorps SFRS13, anticorps SRp38, anticorps SRrp40, anticorps TASR, anticorps TASR1, anticorps TASR2, anticorps Fusip1, anticorps NSSR1, anticorps NSSR2, anticorps Nssr, anticorps Sfrs13a, anticorps Srsf13a, anticorps fusip1, anticorps fusip2, anticorps nssr, anticorps sfrs13, anticorps sfrs13a, anticorps srp38, anticorps srrp40, anticorps tasr, anticorps tasr1, anticorps tasr2, anticorps serine and arginine rich splicing factor 10, anticorps serine/arginine-rich splicing factor 10, anticorps serine/arginine-rich splicing factor 10 S homeolog, anticorps SRSF10, anticorps Srsf10, anticorps srsf10.S

Sujet:

Synonyms: 40 kDa SR repressor protein, 40 kDa SR-repressor protein, Anti TLS associated protein with SR repeats, arginine/serine-rich 13A, FUS interacting protein serine arginine rich 1, FUS interacting protein serine arginine rich 2, FUS interacting serine arginine rich protein 1, FUS-interacting serine-arginine-rich protein 1, FUSIP1, FUSIP2, NSSR, OTTHUMP00000015774, Serine arginine repressor protein 40 kDa, Serine/arginine-rich splicing factor 10, SFRS13, SFRS13A, Splicing factor, Splicing factor arginine serine rich 13, Splicing factor SRp38, SRp38, SRp40, SRrp40, SRS10_HUMAN, Srsf10, TASR, TASR1, TASR2, TLS associated protein TASR1, TLS associated protein TASR2, TLS associated protein with Ser Arg repeats, TLS associated protein with SR repeats, TLS associated serine arginine protein 1, TLS associated serine arginine protein 2, TLS associated serine arginine protein, TLS associated SR protein, TLS-associated protein with Ser-Arg repeats, TLS-associated protein with SR repeats, TLS-associated serine-arginine protein, TLS-associated SR protein.

Background: FUSIP1 is a member of the Serine/Arginine (SR) family of splicing factors. Members of the SR family all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. SR factors are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Expressed in a variety of tissues with low expression in kidney, liver and heart, FUSIP1 localizes to the cytoplasm and nuclear speckles. In its dephosphorylated form (occurring during M phase of the cell cycle), FUSIP1 functions as a potent general repressor of pre-mRNA splicing and can interact with U1 SnRNP 70. In its phosphorylated form, FUSIP1 interacts with Tra-2 and, together, they may cooperate in the regulation of splicing. Four isoforms exist for FUSIP1. In neurons, FUSIP1 isoforms may act to either positively or negatively regulate alternative splicing.

ID gène: 10772

Pathways: Ribonucleoprotein Complex Subunit Organization