GPR124 anticorps (AA 351-450) (Biotin)

N° du produit ABIN1701283

Détail du produit anti-GPR124 anticorps (Biotin)

Antigène: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Épitope: AA 351-450

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR124 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human G protein coupled receptor 124

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GPR124

Antigène: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Autre désignation: GPR124 (GPR124 Produits)

Synonymes: anticorps TEM5, anticorps 8430414O08Rik, anticorps 9530074E10Rik, anticorps Tem5, anticorps mKIAA1531, anticorps MGC69043, anticorps si:dkey-208c22.2, anticorps GPR124, anticorps adhesion G protein-coupled receptor A2, anticorps adhesion G protein-coupled receptor A2 L homeolog, anticorps G-protein coupled receptor 124, anticorps ADGRA2, anticorps Adgra2, anticorps adgra2.L, anticorps adgra2, anticorps LOC616111

Sujet:

Synonyms: DKFZp434C211, DKFZp434J0911, FLJ14390, G protein coupled receptor 124, G-protein coupled receptor 124, GP124_HUMAN, GPR 124, GPR124, KIAA1531, TEM 5, TEM5, Tumor endothelial marker 5, Tumor endothelial marker 5 precursor, GPCR GPR124, Adhesion G protein-coupled receptor A2, ADGRA2.

Background: Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.

ID gène: 25960

UniProt: Q96PE1