BSPRY anticorps (AA 251-350) (Cy5)

N° du produit ABIN1703832

Détail du produit anti-BSPRY anticorps (Cy5)

Antigène: BSPRY (B-Box and SPRY Domain Containing (BSPRY))

Épitope: AA 251-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BSPRY est conjugé à/à la Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BSPRY

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BSPRY

Antigène: BSPRY (B-Box and SPRY Domain Containing (BSPRY))

Autre désignation: BSPRY (BSPRY Produits)

Synonymes: anticorps B-box and SPRY domain containing, anticorps BSPRY, anticorps Bspry

Sujet:

Synonyms: B box and SPRY domain containing, B box and SPRY domain containing protein, B box and SPRY domain-containing protein,B-box and SPRY domain containing, Bspry, BSPRY_HUMAN, FLJ20150, Zetin 1.

Background: BSPRY is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.