GEMIN6 anticorps (AA 21-120) (Cy5)
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- Antigène Voir toutes GEMIN6 Anticorps
- GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
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Épitope
- AA 21-120
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GEMIN6 est conjugé à/à la Cy5
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Humain, Rat
- Homologie
- Mouse,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Gemin 6
- Isotype
- IgG
- Top Product
- Discover our top product GEMIN6 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))
- Autre désignation
- Gemin 6 (GEMIN6 Produits)
- Synonymes
- anticorps 2610019B15Rik, anticorps 2810470M17Rik, anticorps gemin6, anticorps gem nuclear organelle associated protein 6, anticorps gem (nuclear organelle) associated protein 6, anticorps gem nuclear organelle associated protein 6 S homeolog, anticorps GEMIN6, anticorps Gemin6, anticorps gemin6.S
- Sujet
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Synonyms: FLJ23459, Gemin6, Gemin-6, Gem nuclear organelle associated protein 6, Gem-associated protein 6, GEMI6, GEMI6_HUMAN, Gemin-6, GEMIN6, SIP2.
Background: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).
- ID gène
- 79833
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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