CHTOP anticorps (AA 31-130) (Cy5)

N° du produit ABIN1704246

Détail du produit anti-CHTOP anticorps (Cy5)

Antigène: CHTOP (Chromatin Target of PRMT1 (CHTOP))

Épitope: AA 31-130

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHTOP est conjugé à/à la Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human C1orf77

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CHTOP

Antigène: CHTOP (Chromatin Target of PRMT1 (CHTOP))

Autre désignation: C1orf77 (CHTOP Produits)

Synonymes: anticorps C1orf77, anticorps FL-SRAG, anticorps FOP, anticorps RP1-178F15.2, anticorps SRAG, anticorps SRAG-3, anticorps SRAG-5, anticorps pp7704, anticorps 2500003M10Rik, anticorps C81330, anticorps Fop, anticorps Srag, anticorps C25H1orf77, anticorps C3H1orf77, anticorps c1orf77, anticorps chtop, anticorps fop, anticorps srag, anticorps fb17a05, anticorps wu:fb17a05, anticorps wu:fi05e09, anticorps zgc:55292, anticorps zgc:153909, anticorps chromatin target of PRMT1, anticorps chromatin target of PRMT1 S homeolog, anticorps chromatin target of PRMT1 protein, anticorps chromatin target of PRMT1a, anticorps chromatin target of PRMT1b, anticorps CHTOP, anticorps Chtop, anticorps chtop.S, anticorps LOC100344922, anticorps chtopa, anticorps chtopb

Sujet:

Synonyms: Chromatin target of PRMT1 protein, Chromosome 1 open reading frame 77, CHTOP, CHTOP_HUMAN, DKFZp547E1010, FOP, Friend of PRMT1 protein, MGC131924, MGC86949, OTTHUMP00000035122, OTTHUMP00000035123, Pp7704, RP1 178F15.2, Small arginine- and glycine-rich protein, Small protein rich in arginine and glycine, SRAG.

Background: C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

ID gène: 26097