FXYD6 anticorps (AA 15-75) (Cy5.5)
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- Antigène Voir toutes FXYD6 Anticorps
- FXYD6 (FXYD Domain Containing Ion Transport Regulator 6 (FXYD6))
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Épitope
- AA 15-75
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FXYD6 est conjugé à/à la Cy5.5
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human FXYD6
- Isotype
- IgG
- Top Product
- Discover our top product FXYD6 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- FXYD6 (FXYD Domain Containing Ion Transport Regulator 6 (FXYD6))
- Autre désignation
- FXYD6 (FXYD6 Produits)
- Synonymes
- anticorps 0610030I18Rik, anticorps Php, anticorps FXYD domain containing ion transport regulator 6, anticorps FXYD domain-containing ion transport regulator 6, anticorps FXYD6, anticorps Fxyd6
- Sujet
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Synonyms: FXYD domain containing ion transport regulator 6, FXYD domain containing ion transport regulator 6 precursor, Phosphohippolin, UNQ521/PRO1056, FXYD6_HUMAN.
Background: The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing seven invariant and six conserved amino acids. Members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD2 (the g subunit of the Na+/K+-ATPase), FXYD3 (Mat8, mammary tumor protein), FXYD4 (CHIF) and FXYD5 (RIC). FXYD6 is expressed in various epithelial cells bordering the endolymph space and in the auditory neurons. FXYD6 co-localizes with Na+/K+-ATPase in the stria vascularis and can be co-immunoprecipitated with Na+/K+-ATPase. After expression, FXYD6 associates with Na+/K+-ATPase alpha1-beta1 and alpha1-beta2 isozymes, which are preferentially expressed in different regions of the inner ear and also with gastric and non-gastric H+/K+-ATPase.
- ID gène
- 53826
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