LIMS2 anticorps (AA 251-341) (HRP)

N° du produit ABIN1711182

Détail du produit anti-LIMS2 anticorps (HRP)

Antigène: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Épitope: AA 251-341

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIMS2 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LIMS2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur LIMS2

Antigène: LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))

Autre désignation: LIMS2 (LIMS2 Produits)

Synonymes: anticorps PINCH2, anticorps PINCH-2, anticorps LIMS1, anticorps LIM and senescent cell antigen like domains 2, anticorps LIM zinc finger domain containing 2, anticorps Lims2, anticorps LIMS2

Sujet:

Synonyms: FLJ10044, ILK binding protein, LIM and senescent cell antigen like domains 2, LIM and senescent cell antigen-like-containing domain protein 2, LIM-like protein 2, LIMS2, LIMS2_HUMAN, Particularly interesting new Cys-His protein 2, PINCH 2, PINCH-2, PINCH2.

Background: Pinch is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is a major part of the growth factor and integrin signaling pathway. Pinch is involved in cell differentiation, proliferation and survival by acting as an effector of integrin and growth factor signaling. It is a cytoplasmic protein expressed in most tissues and consists of five LIM domains, a nuclear localization signal and a nuclear export signal. The PINCH-1/ILK complex is regulated by another member of the Pinch family, PINCH-2, which also forms a complex with ILK.

Pathways: Cell-Cell Junction Organization