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C1orf85 anticorps (AA 51-150) (HRP)

C1ORF85 Reactivité: Humain WB, ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1712013
  • Antigène Voir toutes C1orf85 (C1ORF85) Anticorps
    C1orf85 (C1ORF85) (Chromosome 1 Open Reading Frame 85 (C1ORF85))
    Épitope
    • 14
    • 2
    • 1
    AA 51-150
    Reactivité
    • 14
    • 3
    • 1
    Humain
    Hôte
    • 16
    • 1
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C1orf85 est conjugé à/à la HRP
    Application
    • 17
    • 13
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C1orf85
    Isotype
    IgG
    Top Product
    Discover our top product C1ORF85 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    C1orf85 (C1ORF85) (Chromosome 1 Open Reading Frame 85 (C1ORF85))
    Autre désignation
    C1orf85 (C1ORF85 Produits)
    Synonymes
    anticorps NCU-G1, anticorps C1orf85, anticorps 0610031j06rik, anticorps AB027141, anticorps CA085 protein, anticorps glycosylated lysosomal membrane protein, anticorps glmp, anticorps GLMP, anticorps Glmp
    Sujet

    Synonyms: C1orf85, Chromosome 1 open reading frame 85, Lysosomal protein NCU-G1, NCUG1_HUMAN, PSEC0030, UNQ2553/PRO6182.

    Background: C1orf85, also known as Lysosomal protein NCU-G1, is a 406 amino acid single-pass membrane protein that is highly glycosylated on its amino-terminal end. Transcription of the gene encoding C1orf85 is activated by TFEB, a transcription factor that specifically recognizes and binds E-box sequences. There are two isoforms of C1orf85 that are produced as a result of alternative splicing events. The C1orf85 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

    ID gène
    112770
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