GLUD2 anticorps (PE-Cy5)
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- Antigène Voir toutes GLUD2 Anticorps
- GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GLUD2 est conjugé à/à la PE-Cy5
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Application
- Western Blotting (WB)
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GLUD2
- Isotype
- IgG
- Top Product
- Discover our top product GLUD2 Anticorps primaire
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- Indications d'application
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))
- Autre désignation
- GLUD2 (GLUD2 Produits)
- Synonymes
- anticorps GDH2, anticorps GLUDP1, anticorps GLUTAMATE DEHYDROGENASE 2, anticorps T2I1.150, anticorps T2I1_150, anticorps glutamate dehydrogenase 2, anticorps glutamate dehydrogenase 2, anticorps glutamate dehydrogenase, anticorps GLUD2, anticorps GDH2, anticorps NP_RS03950
- Sujet
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Synonyms: GDH 2, GDH, GDH2, GLUDP1, Glutamate dehydrogenase 2, Glutamate dehydrogenase 2 mitochondrial, Glutamate dehydrogenase pseudogene 1.
Background: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.
- ID gène
- 2747
- Pathways
- Synaptic Membrane
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