AFAP1L2 anticorps (AA 751-818)

N° du produit ABIN1713696

Détail du produit anti-AFAP1L2 anticorps

Antigène: AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))

Épitope: AA 751-818

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFAP1L2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Souris

Homologie: Human,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human AFAP1L2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur AFAP1L2

Antigène: AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))

Autre désignation: AFAP1L2 (AFAP1L2 Produits)

Synonymes: anticorps KIAA1914, anticorps XB130, anticorps AU041783, anticorps C86904, anticorps mKIAA1914, anticorps RGD1310668, anticorps actin filament associated protein 1 like 2, anticorps actin filament associated protein 1-like 2, anticorps AFAP1L2, anticorps Afap1l2

Sujet:

Synonyms: KIAA1914, XB130, Actin filament-associated protein 1-like 2, AF1L2_HUMAN, AFAP1-like protein 2, afap1l2.

Background: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.

Pathways: EGFR Signaling Pathway