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SCIMP anticorps (AA 1-100)

SCIMP Reactivité: Humain IF (cc), IF (p), ELISA, ICC, IHC (fro), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713711
  • Antigène Voir toutes SCIMP Anticorps
    SCIMP (SLP Adaptor and CSK Interacting Membrane Protein (SCIMP))
    Épitope
    • 14
    • 4
    AA 1-100
    Reactivité
    Humain
    Hôte
    • 18
    • 4
    Lapin
    Clonalité
    • 18
    • 4
    Polyclonal
    Conjugué
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SCIMP est non-conjugé
    Application
    • 12
    • 12
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C17orf87
    Isotype
    IgG
    Top Product
    Discover our top product SCIMP Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SCIMP (SLP Adaptor and CSK Interacting Membrane Protein (SCIMP))
    Autre désignation
    C17orf87 (SCIMP Produits)
    Synonymes
    anticorps C17orf87, anticorps UNQ5783, anticorps A430084P05Rik, anticorps SLP adaptor and CSK interacting membrane protein, anticorps SCIMP, anticorps Scimp
    Sujet

    Synonyms: C17orf87, CQ087_HUMAN, DTFT5783, SCIMP, SLP adaptor and CSK interacting membrane protein, SLP65/SLP76, Transmembrane protein C17orf87, UNQ5783, UNQ5783/PRO16090.

    Background: C17orf87 (chromosome 17 open reading frame 87) is a 145 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

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