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POLH anticorps (AA 51-160)

POLH Reactivité: Humain WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713764
  • Antigène Voir toutes POLH Anticorps
    POLH (Polymerase (DNA Directed), eta (POLH))
    Épitope
    • 14
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 51-160
    Reactivité
    • 42
    • 12
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 42
    • 3
    Lapin
    Clonalité
    • 44
    • 1
    Polyclonal
    Conjugué
    • 18
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLH est non-conjugé
    Application
    • 32
    • 12
    • 12
    • 11
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DNA polymerase eta
    Isotype
    IgG
    Top Product
    Discover our top product POLH Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    POLH (Polymerase (DNA Directed), eta (POLH))
    Autre désignation
    DNA polymerase eta (POLH Produits)
    Synonymes
    anticorps POLH, anticorps fc50a12, anticorps wu:fc50a12, anticorps zgc:136881, anticorps zgc:152642, anticorps RAD30, anticorps RAD30A, anticorps XP-V, anticorps XPV, anticorps polymerase (DNA directed), eta S homeolog, anticorps DNA polymerase eta, anticorps polymerase (DNA directed), eta, anticorps putative DNA polymerase eta, anticorps polymerase (DNA directed), eta (RAD 30 related), anticorps polh.S, anticorps POLH, anticorps polh, anticorps Tb10.70.6190, anticorps LINJ_21_0690, anticorps Polh, anticorps LOC100443019
    Sujet

    Synonyms: DNA polymerase eta, FLJ16395, FLJ21978, POLH, POLH_HUMAN, polymerase DNA directed eta, RAD30, RAD30 homolog A, RAD30A, Xeroderma pigmentosum variant type protein, XP V, XPV.

    Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.

    ID gène
    5429
    Pathways
    Réparation de l'ADN
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