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DTX2 anticorps (AA 331-430)

DTX2 Reactivité: Humain WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713769
  • Antigène Voir toutes DTX2 Anticorps
    DTX2 (Deltex Homolog 2 (DTX2))
    Épitope
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 331-430
    Reactivité
    • 34
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 2
    • 1
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DTX2 est non-conjugé
    Application
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Horse,Zebrafish
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DTX2
    Isotype
    IgG
    Top Product
    Discover our top product DTX2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DTX2 (Deltex Homolog 2 (DTX2))
    Autre désignation
    DTX2 (DTX2 Produits)
    Synonymes
    anticorps RNF58, anticorps 2610524D08Rik, anticorps AA408415, anticorps AU022494, anticorps Deltex2, anticorps dtx2, anticorps deltex E3 ubiquitin ligase 2, anticorps probable E3 ubiquitin-protein ligase DTX2, anticorps deltex 2, E3 ubiquitin ligase, anticorps deltex 2, E3 ubiquitin ligase S homeolog, anticorps DTX2, anticorps Dtx2, anticorps LOC735784, anticorps LOC747633, anticorps dtx2, anticorps dtx2.S
    Sujet

    Synonyms: Deltex 2, Deltex2, hDTX2, Highly similar to hPMSR6 [H.sapiens], Protein deltex 2, RING finger protein 58, RNF58, Zinc ion binding protein, DTX2_HUMAN.

    Background: DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context, mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.

    ID gène
    113878
    Pathways
    Signalisation Notch
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