DUSP5 anticorps (AA 221-320)

N° du produit ABIN1713770

Détail du produit anti-DUSP5 anticorps

Antigène: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Épitope: AA 221-320

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DUSP5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-DUSP5 (ABIN1713770)

Cai, Chen, Han, He, Chen, Chen, Yang, Wu, Zeng, Zou, Liang, Dai, Jiang, Zhong: "Down-regulation of dual-specificity phosphatase 5 predicts poor prognosis of patients with prostate cancer." dans: International journal of clinical and experimental medicine, Vol. 8, Issue 3, pp. 4186-94, (2015) (PubMed).

Détails sur DUSP5

Antigène: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Autre désignation: DUSP5 (DUSP5 Produits)

Synonymes: anticorps DUSP5, anticorps wu:fc03b11, anticorps wu:fc86e02, anticorps MGC84792, anticorps dusp, anticorps hvh3, anticorps DUSP, anticorps HVH3, anticorps Cpg21, anticorps Gm337, anticorps dual specificity phosphatase 5, anticorps dual specificity phosphatase 5 S homeolog, anticorps DUSP5, anticorps dusp5, anticorps dusp5.S, anticorps Dusp5

Sujet:

Synonyms: Dual specicity protein phosphatase 5, Dual specicity protein phosphatase hVH 3, Dual specicity protein phosphatase hVH3, DUSP 5, DUSP, HVH 3, HVH3, Serine/threonine specic protein phosphatase, VH 3, VH1 like phosphatase 3, VH3, DUS5_HUMAN.

Background: Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), MKP-2, MKP-3, MKP-4, MKP-5, MKP-6, MKP-7, MKP-X, VHR, VHY, PAC1, hVH-3 (B23), hVH-5, PYST2, DUSP1, DUSP5, DUSP8, PIR1 and SKRP1. DUSP5 is a nuclear phosphoprotein that displays phosphatase activity toward several different substrates. It shows the highest relative activity toward ERK1.

ID gène: 1847