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NOB1 anticorps

NOB1 Reactivité: Humain, Souris, Rat WB, IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1713871
  • Antigène Voir toutes NOB1 Anticorps
    NOB1 (RNA-Binding Protein NOB1 (NOB1))
    Reactivité
    • 52
    • 23
    • 20
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 51
    • 2
    Lapin
    Clonalité
    • 51
    • 2
    Polyclonal
    Conjugué
    • 20
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NOB1 est non-conjugé
    Application
    • 43
    • 20
    • 12
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human NOB1
    Isotype
    IgG
    Top Product
    Discover our top product NOB1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    NOB1 (RNA-Binding Protein NOB1 (NOB1))
    Autre désignation
    NOB1 (NOB1 Produits)
    Synonymes
    anticorps MEE6.26, anticorps MEE6_26, anticorps Nob1p, anticorps fc27e05, anticorps si:ch73-167i17.3, anticorps wu:fc27e05, anticorps ART-4, anticorps MST158, anticorps NOB1P, anticorps PSMD8BP1, anticorps 1700021I09Rik, anticorps Psmd8bp1, anticorps NIN1/PSMD8 binding protein 1 homolog, anticorps RNA-binding NOB1-like protein, anticorps RNA-binding protein nob1, anticorps RNA-binding protein NOB1, anticorps NIN1/RPN12 binding protein 1 homolog S homeolog, anticorps NIN1/RPN12 binding protein 1 homolog (S. cerevisiae), anticorps NIN1/RPN12 binding protein 1 homolog, anticorps NOB1, anticorps AT5G41190, anticorps EDI_130960, anticorps CpipJ_CPIJ012739, anticorps BDBG_01281, anticorps PAAG_04204, anticorps PITG_13300, anticorps nob1.S, anticorps nob1, anticorps Nob1
    Sujet

    Synonyms: Adenocarcinoma antigen recognized by T lymphocytes 4, ART4, MST158, MSTP158, Nin one binding protein, NIN1/RPN12 binding protein 1 homolog S. cerevisiae, nob1, NOB1_HUMAN, NOB1P, Phosphorylation regulatory protein HP-10, Protein ART-4, Protein ART4, PSMD8 binding protein 1, PSMD8BP1, RNA binding protein NOB1, RNA-binding protein NOB1.

    Background: NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates.

    ID gène
    28987
    Pathways
    Protein targeting to Nucleus
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