NOB1 anticorps

N° du produit ABIN1713871

Détail du produit anti-NOB1 anticorps

Antigène: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NOB1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur NOB1

Antigène: NOB1 (RNA-Binding Protein NOB1 (NOB1))

Autre désignation: NOB1 (NOB1 Produits)

Synonymes: anticorps MEE6.26, anticorps MEE6_26, anticorps Nob1p, anticorps fc27e05, anticorps si:ch73-167i17.3, anticorps wu:fc27e05, anticorps ART-4, anticorps MST158, anticorps NOB1P, anticorps PSMD8BP1, anticorps 1700021I09Rik, anticorps Psmd8bp1, anticorps NIN1/PSMD8 binding protein 1 homolog, anticorps RNA-binding NOB1-like protein, anticorps RNA-binding protein nob1, anticorps RNA-binding protein NOB1, anticorps NIN1/RPN12 binding protein 1 homolog S homeolog, anticorps NIN1/RPN12 binding protein 1 homolog (S. cerevisiae), anticorps NIN1/RPN12 binding protein 1 homolog, anticorps NOB1, anticorps AT5G41190, anticorps EDI_130960, anticorps CpipJ_CPIJ012739, anticorps BDBG_01281, anticorps PAAG_04204, anticorps PITG_13300, anticorps nob1.S, anticorps nob1, anticorps Nob1

Sujet:

Synonyms: Adenocarcinoma antigen recognized by T lymphocytes 4, ART4, MST158, MSTP158, Nin one binding protein, NIN1/RPN12 binding protein 1 homolog S. cerevisiae, nob1, NOB1_HUMAN, NOB1P, Phosphorylation regulatory protein HP-10, Protein ART-4, Protein ART4, PSMD8 binding protein 1, PSMD8BP1, RNA binding protein NOB1, RNA-binding protein NOB1.

Background: NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates.

ID gène: 28987

Pathways: Protein targeting to Nucleus